
"Microsoft .NET ClickOnce Launch Utility has encountered a problem and needs to close. We are sorry for the inconvenience". who is this "we" who is sorry? are they sorry enough to actual do something about it besides apologize? the details say applaunch.exe has a system.io.fileloadexception. this seems to be another example of microsoft putting out sloppy code. my google search shows nobody else reporting this problem. guess I'm just special :p
part 2 of why ClickOnce sucks? Joe Wirtley has already covered this very nicely - I found his post when I ran into the same problems as he did and I suggest you read it: ClickOnce and Bogus Required Assemblies.